CBC PUBLICATIONS Funded by CBC AWARDS
Alhasan AH, Kim DY, Daniel WL, Watson E, Meeks JJ, Thaxton CS, Mirkin CA. Scanometric MicroRNA Array Profiling of Prostate Cancer Markers Using Spherical Nucleic Acid-Gold Nanoparticle Conjugates. Anal Chem. 2012 May 1;84(9):4153-60. (PubMed)
Ament SA, Wang Y, Chen CC, Blatti CA, Hong F, Liang ZS, Negre N, White KP, Rodriguez-Zas SL, Mizzen CA, Sinha S, Zhong S, Robinson GE. The transcription factor ultraspiracle influences honey bee social behavior and behavior-related gene expression. PLoS Genet. 2012 Mar;8(3):e1002596. (PubMed)
Arslan SY, Son KN, Lipton HL. The anti-apoptotic Mcl-1 protein controls the type of cell death in Theiler's virus-infected BHK-21 cells. J Virol. 2012 Feb;86(4):1922-9. (PubMed)
Chen S, Ni X, Krinsky BH, Zhang YE, Vibranovski MD, White KP, Long M. Reshaping of global gene expression networks and sex-biased gene expression by integration of a young gene. EMBO J. 2012 Apr 27. doi: 10.1038/emboj.2012.108. [Epub ahead of print] (PubMed)
Chen Y, Negre N, Li Q, Mieczkowska JO, Slattery M, Liu T, Zhang Y, Kim TK, He HH, Zieba J, Ruan Y, Bickel PJ, Myers RM, Wold BJ, White KP, Lieb JD, Liu XS. Systematic evaluation of factors influencing ChIP-seq fidelity. Nat Methods. 2012 Apr 22. doi: 10.1038/nmeth.1985. [Epub ahead of print] (PubMed)
Chen Y, Ntai I, Ju KS, Unger M, Zamdborg L, Robinson SJ, Doroghazi JR, Labeda DP, Metcalf WW, Kelleher NL. A Proteomic Survey of Nonribosomal Peptide and Polyketide Biosynthesis in Actinobacteria. J Proteome Res. 2012 Jan 1;11(1):85-94. (PubMed)
Chen Y, Sheng R, Källberg M, Silkov A, Tun MP, Bhardwaj N, Kurilova S, Hall RA, Honig B, Lu H, Cho W. Genome-wide Functional Annotation of Dual-Specificity Protein- and Lipid-Binding Modules that Regulate Protein Interactions. Mol Cell. 2012 Apr 27;46(2):226-37. (PubMed)
Cozen W, Li D, Best T, Van Den Berg DJ, Gourraud PA, Cortessis VK, Skol AD, Mack TM, Glaser SL, Weiss LM, Nathwani BN, Bhatia S, Schumacher FR, Edlund CK, Hwang AE, Slager SL, Fredericksen ZS, Strong LC, Habermann TM, Link BK, Cerhan JR, Robison LL, Conti DV, Onel K. A genome-wide meta-analysis of nodular sclerosis Hodgkin lymphoma identifies risk loci at 6p21.32. Blood. 2012 Jan 12;119(2):469-75. (PubMed)
Curtis MW, Budyn E, Desai TA, Samarel AM, Russell B. Microdomain heterogeneity in 3D affects the mechanics of neonatal cardiac myocyte contraction. Biomech Model Mechanobiol. 2012 Mar 11. [Epub ahead of print] (PubMed)
Deng X, Sun F, Ji Q, Liang H, Missiakas D, Lan L, He C. Expression of multidrug resistance efflux pump gene norA is iron-responsive in Staphylococcus aureus. J Bacteriol. 2012 Apr;194(7):1753-62. (PubMed)
Doçi CL, Mankame TP, Langerman A, Ostler KR, Kanteti R, Best T, Onel K, Godley LA, Salgia R, Lingen MW. Characterization of NOL7 Gene Point Mutations, Promoter Methylation, and Protein Expression in Cervical Cancer. Int J Gynecol Pathol. 2012 Jan;31(1):15-24. (PubMed)
Dombeck DA, Reiser MB. Real neuroscience in virtual worlds. Curr Opin Neurobiol. 2012 Feb;22(1):3-10. (PubMed)
Doré LC, Chlon TM, Brown CD, White KP, Crispino JD. Chromatin occupancy analysis reveals genome-wide GATA factor switching during hematopoiesis. Blood. 2012 Mar 1. [Epub ahead of print] (Blood)
Duan Y, Learoyd J, Meliton AY, Leff AR, Zhu X. Inhibition of Pyk2 blocks lung inflammation and injury in a mouse model of acute lung injury. Respir Res. 2012 Jan 18;13(1):4. (PubMed)
Foshay KM, Looney TJ, Chari S, Mao FF, Lee JH, Zhang L, Fernandes CJ, Baker SW, Clift KL, Gaetz J, Di CG, Xiang AP, Lahn BT. Embryonic Stem Cells Induce Pluripotency in Somatic Cell Fusion through Biphasic Reprogramming. Mol Cell. 2012 Apr 27;46(2):159-70. (PubMed)
Frank SA, Rosner MR. Nonheritable Cellular Variability Accelerates the Evolutionary Processes of Cancer. PLoS Biol. 2012 10(4): e1001296. (PLoS Biology)
Gaetz J, Clift KL, Fernandes CJ, Mao FF, Lee JH, Zhang L, Baker SW, Looney TJ, Foshay KM, Yu WH, Xiang AP, Lahn BT. Evidence for a critical role of gene occlusion in cell fate restriction. Cell Res. 2012 May;22(5):848-58. (PubMed)
Grossman RL, White KP. A Vision for a Biomedical Cloud. J Intern Med. 2012 Feb;271(2):122-30. doi: 10.1111/j.1365-2796.2011.02491.x. (PubMed)
Ji Q, Zhang L, Sun F, Deng X, Liang H, Bae T, He C. Staphylococcus aureus CymR is a new thiol-based oxidation-sensing regulator of stress resistance and oxidative response. J Biol Chem. 2012 May 2. [Epub ahead of print] (PubMed)
Kellie JF, Catherman AD, Durbin KR, Tran JC, Tipton JD, Norris JL, Witkowski CE, Thomas PM, Kelleher NL. Robust Analysis of the Yeast Proteome under 50 kDa by Molecular Weight-Based Fractionation and Top-Down Mass Spectrometry. Anal Chem. 2012 Jan 3;84(1):209-15. (PubMed)
Kim Guisbert KS, Zhang Y, Flatow J, Hurtado S, Staley JP, Lin S, Sontheimer EJ. Meiosis-induced alterations in transcript architecture and noncoding RNA expression in S. cerevisiae. RNA. 2012 Apr 26. [Epub ahead of print] (PubMed)
Lee H, Torres J, Truong L, Chaudhuri R, Mittal A, Johnson ME. Reducing agents affect inhibitory activities of compounds: Results from multiple drug targets. Anal Biochem. 2012 Jan 18;423(1):46-53. (PubMed)
Liang H, Deng X, Ji Q, Sun F, Shen T, He C. Pseudomonas aeruginosa global regulator VqsR directly inhibits QscR to control quorum-sensing and virulence gene expression. J Bacteriol. 2012 Apr 13. [Epub ahead of print] (PubMed)
Lu A, Atkinson IC, Zhou XJ, Thulborn KR. PCr/ATP ratio mapping of the human head by simultaneously imaging of multiple spectral peaks with interleaved excitations and flexible twisted projection imaging readout trajectories at 9.4 T. Magn Reson Med. 2012 Apr 23. doi: 10.1002/mrm.24281. [Epub ahead of print] (PubMed)
Maienschein-Cline M, Zhou J, White KP, Sciammas R, Dinner AR. Discovering Transcription Factor Regulatory Targets Using Gene Expression and Binding Data. Bioinformatics. 2012 Jan 15;28(2):206-13. (PubMed)
McMullen PD, Aprison EZ, Winter PB, Amaral LA, Morimoto RI, Ruvinsky I. Macro-level Modeling of the Response of C. elegans Reproduction to Chronic Heat Stress. PLoS Comput Biol. 2012 Jan;8(1):e1002338. (PubMed)
Nogueira V, Sundararajan D, Kwan JM, Peng XD, Sarvepalli N, Sonenberg N, Hay N. Akt-dependent Skp2 mRNA translation is required for exiting contact inhibition, oncogenesis, and adipogenesis. EMBO J. 2012 Feb 3;31(5):1134-46. (PubMed)
Peek CB, Ramsey KM, Marcheva B, Bass J. Nutrient sensing and the circadian clock. Trends Endocrinol Metab. 2012 Mar 15. [Epub ahead of print] (PubMed)
Peláez N, Carthew RW. Biological Robustness and the Role of MicroRNAs: A Network Perspective. Curr Top Dev Biol. 2012;99:237-55. (PubMed)
Prigodich AE, Randeria PS, Briley WE, Kim NJ, Daniel WL, Giljohann DA, Mirkin CA. Multiplexed Nanoflares: mRNA Detection in Live Cells. Anal Chem. 2012 Feb 21;84(4):2062-6. (PubMed)
Rajapakse HE, Miller LW. Time-resolved luminescence resonance energy transfer imaging of protein-protein interactions in living cells. Methods Enzymol. 2012;505:329-45. (PubMed)
Rudra JS, Sun T, Bird KC, Daniels MD, Gasiorowski JZ, Chong AS, Collier JH. Modulating Adaptive Immune Responses to Peptide Self-Assemblies. ACS Nano. 2012 Feb 28;6(2):1557-64. (PubMed)
Shepard JA, Stevans AC, Holland S, Wang CE, Shikanov A, Shea LD. Hydrogel design for supporting neurite outgrowth and promoting gene delivery to maximize neurite extension. Biotechnol Bioeng. 2012 Mar;109(3):830-9. doi: 10.1002/bit.24355. (PubMed)
Shvartsburg AA, Zheng Y, Smith RD, Kelleher NL. Ion Mobility Separation of Variant Histone Tails Extending to the "Middle-Down" Range. Anal Chem. 2012 May 15;84(10):4271-6. (PubMed)
Singer BF, Scott-Railton J, Vezina P. Unpredictable saccharin reinforcement enhances locomotor responding to amphetamine. Behav Brain Res. 2012 Jan 1;226(1):340-4. (PubMed)
Siu KT, Rosner MR, Minella AC. An integrated view of cyclin E function and regulation. Cell Cycle. 2012 Jan 1;11(1):57-64. (PubMed)
Strickland D, Lin Y, Wagner E, Hope CM, Zayner J, Antoniou C, Sosnick TR, Weiss EL, Glotzer M. TULIPs: tunable, light-controlled interacting protein tags for cell biology. Nat Methods. 2012 Mar 4;9(4):379-84. (PubMed)
Sun F, Ji Q, Jones MB, Deng X, Liang H, Frank B, Telser J, Peterson SN, Bae T, He C. AirSR, a [2Fe-2S] Cluster-Containing Two-Component System, Mediates Global Oxygen Sensing and Redox Signaling in Staphylococcus aureus. J Am Chem Soc. 2012 Jan 11;134(1):305-14. (PubMed)
Sun F, Liang H, Kong X, Xie S, Cho H, Deng X, Ji Q, Zhang H, Alvarez S, Hicks LM, Bae T, Luo C, Jiang H, He C. Quorum-sensing agr mediates bacterial oxidation response via an intramolecular disulfide redox switch in the response regulator AgrA. Proc Natl Acad Sci U S A. 2012 May 14. [Epub ahead of print] (PubMed)
Sylvester JE, Bray TS, Kron SJ. Annotator: Post-processing Software for generating function-based signatures from quantitative mass spectrometry. J Proteome Res. 2012 Mar 2;11(3):1521-36. (PubMed)
Thulborn KR, Atkinson IC, Lu A. Metabolic Magnetic Resonance Imaging: A Case for Bioscales in Medicine. Functional Neuroradiology. 2012, Part 7, 911-928. (Springerlink)
Tipton JD, Tran JC, Catherman AD, Ahlf DR, Durbin KR, Lee JE, Kellie JF, Kelleher NL, Hendrickson CL, Marshall AG. Nano-LC FTICR Tandem Mass Spectrometry for Top-Down Proteomics: Routine Baseline Unit Mass Resolution of Whole Cell Lysate Proteins up to 72 kDa. Anal Chem. Mar 6;84(5):2111-7. (PubMed)
Vagstad AL, Bumpus SB, Belecki K, Kelleher NL, Townsend CA. Interrogation of Global Active Site Occupancy of a Fungal Iterative Polyketide Synthase Reveals Strategies for Maintaining Biosynthetic Fidelity. J Am Chem Soc. 2012 Apr 18;134(15):6865-77. (PubMed)
Weiss MS, Bernabé BP, Shikanov A, Bluver DA, Mui MD, Shin S, Broadbelt LJ, Shea LD. The impact of adhesion peptides within hydrogels on the phenotype and signaling of normal and cancerous mammary epithelial cells. Biomaterials. 2012 May;33(13):3548-59. (PubMed)
Yin P, Roqueiro D, Huang L, Owen JK, Xie A, Navarro A, Monsivais D, Coon JS, Kim JJ, Dai Y, Bulun SE. Genome-Wide Progesterone Receptor Binding: Cell Type-Specific and Shared Mechanisms in T47D Breast Cancer Cells and Primary Leiomyoma Cells. PLoS ONE. 2012 7(1): e29021. doi:10.1371/journal.pone.0029021 (PLoS One)
Yuan H, Chiang CY, Cheng J, Salzmann V, Yamashita YM. Regulation of cyclin A localization downstream of Par-1 function is critical for the centrosome orientation checkpoint in Drosophila male germline stem cells. Dev Biol. 2012 Jan 1;361(1):57-67. (PubMed)
ARCHIVES
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Al-Dhaheri M, Wu J, Skliris GP, Li J, Higashimato K, Wang Y, White KP, Lambert P, Zhu Y, Murphy L, Xu W. CARM1 is an important determinant of ER{alpha}-dependent breast cancer cell differentiation and proliferation in breast cancer cells. Cancer Res. 2011 Mar 15;71(6):2118-28. (PubMed)
Ames BD, Haynes SW, Gao X, Evans BS, Kelleher NL, Tang Y, Walsh CT. Complexity Generation in Fungal Peptidyl Alkaloid Biosynthesis: Oxidation of Fumiquinazoline A to the Heptacyclic Hemiaminal Fumiquinazoline C by the Flavoenzyme Af12070 from Aspergillus fumigatus. Biochemistry. 2011 Oct 11;50(40):8756-69. (PubMed)
Atkinson IC, Lu A, Thulborn KR. Clinically constrained optimization of flexTPI acquisition parameters for the tissue sodium concentration bioscale. Magn Reson Med. 2011 Oct;66(4):1089-99. (PubMed)
Atkinson IC, Lu A, Thulborn KR. Preserving the accuracy and resolution of the sodium bioscale from quantitative sodium MRI during intrasubject alignment across longitudinal studies. Magn Reson Med. 2011 Dec 2. [Epub ahead of print] (PubMed)
Bai H, Sun M, Ghosh P, Hatfull GF, Grindley ND, Marko JF. Single-molecule analysis reveals the molecular bearing mechanism of DNA strand exchange by a serine recombinase. Proc Natl Acad Sci U S A. 2011 May 3;108(18):7419-24. (PubMed)
Bellis AD, Bernabé BP, Weiss MS, Yarrington ME, Barbolina MV, Pannier AK, Jeruss JS, Broadbelt LJ, Shea LD. Cellular arrays for large-scale analysis of transcription factor activity. Biotechnol Bioeng. 2011 Feb;108(2):395-403. (PubMed)
Brugarolas P, Duguid EM, Zhang W, Poor CB, He C. Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus. Acta Cryst. 2011 D67, 707-715. (Online)
Chaudhuri R, Tang S, Zhao G, Lu H, Case DA, Johnson ME. Comparison of SARS and NL63 Papain-Like Protease Binding Sites and Binding Site Dynamics: Inhibitor Design Implications. J Mol Biol. 2011 Nov 25;414(2):272-88. (PubMed)
Chen ZX, Zhang YE, Vibranovski M, Luo J, Gao G, Long M. Deficiency of X-linked inverted duplicates with male-biased expression and the underlying evolutionary mechanisms in the Drosophila genome. Mol Biol Evol. 2011 Oct;28(10):2823-32. (PubMed)
Cheng J, Tiyaboonchai A, Yamashita YM, Hunt AJ. Asymmetric division of cyst stem cells in Drosophila testis is ensured by anaphase spindle repositioning. Development. 2011 Mar;138(5):831-7. (PubMed)
Chow CR, Yau DM, Kozasa T. p115RhoGEF. UCSD-Nature Molecule Pages. 2011. (doi: 10.1038/mp.a000008.01)
Colwill K; Renewable Protein Binder Working Group; In vitro Antibody Consortium, Persson H, Jarvik NE, Wyrzucki A, Wojcik J, Koide A, Kossiakoff AA, Koide S, Sidhu S, Dyson MR, Pershad K, Pavlovic JD, Karatt-Vellatt A, Schofield DJ, Kay BK, McCafferty J, Mersmann M, Meier D, Mersmann J, Helmsing S, Hust M, Dübel S; Monash Antibody Technologies Facility, Berkowicz S, Freemantle A, Spiegel M, Sawyer A, Layton D, Nice E; Pawson Laboratory, Dai A, Rocks O, Williton K, Fellouse FA, Hersi K, Pawson T; Human Protein Atlas, Nilsson P, Sundberg M, Sjöberg R, Sivertsson A, Schwenk JM, Takanen JO, Hober S, Uhlén M; Structural Genomics Consortium, Dahlgren LG, Flores A, Johansson I, Weigelt J, Crombet L, Loppnau P, Kozieradzki I, Cossar D, Arrowsmith CH, Edwards AM, Gräslund S. A roadmap to generate renewable protein binders to the human proteome. Nat Methods. 2011 May 15;8(7):551-8. (PubMed)
Compton PD, Zamdborg L, Thomas PM, Kelleher NL. On the Scalability and Requirements of Whole Protein Mass Spectrometry. Anal Chem. 2011 Sep 1;83(17):6868-74. (PubMed)
Cui J, Hao J, Ulanovskaya OA, Dundas J, Liang J, Kozmin SA. Organic Synthesis Toward Small-Molecule Probes and Drugs Special Feature: Creation and manipulation of common functional groups en route to a skeletally diverse chemical library. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):6763-8. (PubMed)
Curtis MW, Russell B. Micromechanical regulation in cardiac myocytes and fibroblasts: implications for tissue remodeling. Pflugers Arch. 2011 Jul;462(1):105-17. (PubMed)
Dai Q, Song CX, Pan T, He C. Syntheses of Two 5-Hydroxymethyl-2'-deoxycytidine Phosphoramidites with TBDMS as the 5-Hydroxymethyl Protecting Group and Their Incorporation into DNA. J Org Chem. 2011 May 20;76(10):4182-8. (PubMed)
Doré LC, Crispino JD. Transcription factor networks in erythroid cell and megakaryocyte development. Blood. 2011 Blood. 2011 Jul 14;118(2):231-9. (PubMed)
Doucette AA, Tran JC, Wall MJ, Fitzsimmons S. Intact proteome fractionation strategies compatible with mass spectrometry. Review. Expert Review of Proteomics. December 2011, Vol. 8, No. 6, Pages 787-800, DOI 10.1586/epr.11.67 (expert-reviews)
Dundas J, Adamian L, Liang J. Structural signatures of enzyme binding pockets from order-independent surface alignment: a study of metalloendopeptidase and NAD binding proteins. J Mol Biol. 2011 Mar 11;406(5):713-29. (PubMed)
ENCODE Project Consortium, Myers RM, Stamatoyannopoulos J, Snyder M, Dunham I, Hardison RC, Bernstein BE, Gingeras TR, Kent WJ, Birney E, Wold B, Crawford GE. A user's guide to the encyclopedia of DNA elements (ENCODE). PLoS Biol. 2011 Apr;9(4):e1001046. (PubMed)
Evans BS, Chen Y, Metcalf WW, Zhao H, Kelleher NL. Directed Evolution of the Nonribosomal Peptide Synthetase AdmK Generates New Andrimid Derivatives In Vivo. Chem Biol. 2011 May 27;18(5):601-7. (PubMed)
Evans BS, Ntai I, Chen Y, Robinson SJ, Kelleher NL. Proteomics-Based Discovery of Koranimine, a Cyclic Imine Natural Product. J Am Chem Soc. May 18;133(19):7316-9. (PubMed)
Fenner D, Odili S, Hong HK, Kobayashi Y, Kohsaka A, Siepka SM, Vitaterna MH, Chen P, Zelent B, Grimsby J, Takahashi JS, Matschinsky FM, Bass J. Generation of ENU diabetes models in the mouse demostrates genotype-specific action of glucokinase activators. J Biol Chem. 2011 Nov 11;286(45):39560-72. (PubMed)
Fu H, Chen H, Zhang X, Qu Y, Marko JF, Yan J. Transition dynamics and selection of the distinct S-DNA and strand unpeeling modes of double helix overstretching. Nucleic Acids Res. 2011 Apr 1;39(8):3473-81. (PubMed)
Gasiorowski JZ, Collier JH. Directed Intermixing in Multicomponent Self-Assembling Biomaterials. Biomacromolecules. 2011 Oct 10;12(10):3549-58. (PubMed)
Gidalevitz T, Prahlad V, Morimoto RI. The stress of protein misfolding: from single cells to multicellular organisms. Cold Spring Harb Perspect Biol. 2011 Jun 1;3(6). (PubMed)
Godley LA, Cunningham J, Dolan ME, Huang RS, Gurbuxani S, McNerney ME, Larson RA, Leong H, Lussier Y, Onel K, Odenike O, Stock W, White KP, Le Beau MM. An integrated genomic approach to the assessment and treatment of acute myeloid leukemia. Semin Oncol. 2011 Apr;38(2):215-24. (Online)
Graham JS, Johnson RC, Marko JF. Concentration-dependent exchange accelerates turnover of proteins bound to double-stranded DNA. Nucleic Acids Res. 2011 Mar 1;39(6):2249-59. (PubMed)
Gu Y, Grossman R. Toward Efficient and Simplified Distributed Data Intensive Computing. IEEE Transactions on Parallel and Distributed Systems. 2011 Volume 22, Issue 6, pages 974-984. (Online)
Hajicek N, Kukimoto-Niino M, Mishima-Tsumagari C, Chow CR, Shirouzu M, Terada T, Patel M, Yokoyama S, Kozasa T. Identification of critical residues in Galpha13 for stimulation of p115RhoGEF activity and the structure of the Galpha13-p115RhoGEF RH domain complex. J Biol Chem. 2011 Jun 10;286(23):20625-36. (PubMed)
Han Y, Khodr CE, Sapru MK, Pedapati J, Bohn MC. A microRNA embedded AAV alpha-synuclein gene silencing vector for dopaminergic neurons. Brain Res. 2011 Apr 22;1386:15-24. (PubMed)
Hay N. Akt isoforms and glucose homeostasis - the leptin connection. Trends Endocrinol Metab. 2011 Feb;22(2):66-73. (PubMed)
Ho JW, Bishop E, Kharchenko PV, Negre N, White KP, Park PJ. ChIP-chip versus ChIP-seq: Lessons for experimental design and data analysis. BMC Genomics. 2011 Feb 28;12(1):134. (PubMed)
Hollenhorst MA, Ntai I, Badet B, Kelleher NL, Walsh CT. A Head-to-Head Comparison of Eneamide and Epoxyamide Inhibitors of Glucosamine-6-Phosphate Synthase from the Dapdiamide Biosynthetic Pathway. Biochemistry. 2011 May 17;50(19):3859-61. (PubMed)
Huang L, Roqueiro, D Dai Y. Analyzing mRNA and microRNA co-expression profiles to identify pathways and their potential regulators in ER+ and ER- breast tumors. Proceedings of 2011 IEEE Engineering in Medicine and Biology Society (EMBC'11). (pdf)
Huang L, Zhao S, Frasor JM, Dai Y. An Integrated Bioinformatics Approach Identifies Elevated Cyclin E2 Expression and E2F Activity as Distinct Features of Tamoxifen Resistant Breast Tumors. PLoS ONE 2011 6(7): e22274. (PLoSOne)
Huang W, Ramsey KM, Marcheva B, Bass J. Circadian rhythms, sleep, and metabolism. J Clin Invest. 2011 Jun 1;121(6):2133-41. (PubMed)
Jia G, Fu Y, Zhao X, Dai Q, Zheng G, Yang Y, Yi C, Lindahl T, Pan T, Yang YG, He C. N6-Methyladenosine in nuclear RNA is a major substrate of the obesity-associated FTO. Nat Chem Biol. 2011 Oct 16;7(12):885-7. (PubMed)
Jungreis I, Lin MF, Spokony R, Chan CS, Negre N, Victorsen A, White KP, Kellis M. Evidence of abundant stop codon readthrough in Drosophila and other Metazoa. Genome Res. 2011 Dec;21(12):2096-113. (PubMed)
Khodr CE, Pedapati J, Han Y, Bohn MC. Inclusion of a portion of the native SNCA 3'UTR reduces toxicity of human S129A SNCA on striatal-projecting dopamine neurons in rat substantia nigra. Dev Neurobiol. 2011 Oct 23. [Epub ahead of print] (PubMed)
Khodr CE, Sapru MK, Pedapati J, Han Y, West NC, Kells AP, Bankiewicz KS, Bohn MC. An alpha- synuclein AAV gene silencing vector ameliorates a behavioral deficit in a rat model of Parkinson’s disease, but displays toxicity in dopamine neurons. Brain Research. 2011 Jun 13;1395:94-107. (PubMed)
Kim AM, Bernhardt ML, Kong BY, Ahn RW, Vogt S, Woodruff TK, O'Halloran TV. Zinc Sparks Are Triggered by Fertilization and Facilitate Cell Cycle Resumption in Mammalian Eggs. ACS Chem Biol. 2011 Jul 15;6(7):716-23. (PubMed)
Klaić L, Trippier PC, Mishra RK, Morimoto RI, Silverman RB. Remarkable Stereospecific Conjugate Additions to the Hsp90 Inhibitor Celastrol. J Am Chem Soc. 2011 Dec 14;133(49):19634-7. (PubMed)
Koldobskaya Y, Duguid EM, Shechner DM, Suslov NB, Ye J, Sidhu SS, Bartel DP, Koide S, Kossiakoff AA, Piccirilli JA. A portable RNA sequence whose recognition by a synthetic antibody facilitates structural determination. Nat Struct Mol Biol. 2011 Jan;18(1):100-6. (PubMed)
Kozasa T, Hajicek N, Chow CR, Suzuki N. Signalling mechanisms of RhoGTPase regulation by the heterotrimeric G proteins G12 and G13. J Biochem. 2011 Oct;150(4):357-69. (PubMed)
Loor G, Kondapalli J, Iwase H, Chandel NS, Waypa GB, Guzy RD, Vanden Hoek TL, Schumacker PT. Mitochondrial oxidant stress triggers cell death in simulated ischemia-reperfusion. Biochim Biophys Acta. 2011 Jul;1813(7):1382-94. (PubMed)
Ludwig MZ, Manu, Kittler R, White KP, Kreitman M. Consequences of eukaryotic enhancer architecture for gene expression dynamics, development, and fitness. PLoS Genet. 2011 Nov;7(11):e1002364. (PubMed)
Maggionia M, Santambrogioa MD, Liang J. GPU-accelerated Chemical Similarity Assessment for Large Scale Databases. Procedia Computer Science Volume 4, 2011, Pages 2007-2016. Proceedings of the International Conference on Computational Science, ICCS 2011. (ScienceDirect)
Marko, J. F. The Mitotic Chromosome: Structure and Mechanics, in Genome Organization and Function in the Cell Nucleus (ed K. Rippe), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. 2011. doi: 10.1002/9783527639991.ch18 (onlinelibrary.wiley)
Martinez-Garcia E, Popovic R, Min DJ, Sweet SM, Thomas PM, Zamdborg L, Heffner A, Will C, Lamy L, Staudt LM, Levens DL, Kelleher NL, Licht JD. The MMSET histone methyl transferase switches global histone methylation and alters gene expression in t(4;14) multiple myeloma cells. Blood. 2011 Jan 6;117(1):211-20. (PubMed)
Maury E, Ramsey KM, Bass J. Sleep, Circadian Rhythms and Metabolism. (Book Chapter). In: Metabolic Basis of Obesity. 2011, 229-255. (Springer)
Molohon KJ, Melby JO, Lee J, Evans BS, Dunbar KL, Bumpus SB, Kelleher NL, Mitchell DA. Structure Determination and Interception of Biosynthetic Intermediates for the Plantazolicin Class of Highly Discriminating Antibiotics. ACS Chem Biol. 2011 Dec 16;6(12):1307-13. (PubMed)
Montavon TJ, Li J, Cabrera-Pardo JR, Mrksich M, Kozmin SA. Three-component reaction discovery enabled by mass spectrometry of self-assembled monolayers. Nat Chem. 2011 Dec 4;4(1):45-51. (PubMed)
Myung JH, Gajjar KA, Saric J, Eddington DT, Hong S. Dendrimer-Mediated Multivalent Binding for the Enhanced Capture of Tumor Cells. Angew Chem Int Ed Engl. 2011 Dec 2;50(49):11769-72. (PubMed)
Neukirch S, Marko JF. Analytical Description of Extension, Torque, and Supercoiling Radius of a Stretched Twisted DNA. Phys Rev Lett. 2011 Apr 1;106(13):138104. (PubMed)
Nègre N, Brown CD, Ma L, Bristow CA, Miller SW, Wagner U, Kheradpour P, Eaton ML, Loriaux P, Sealfon R, Li Z, Ishii H, Spokony RF, Chen J, Hwang L, Cheng C, Auburn RP, Davis MB, Domanus M, Shah PK, Morrison CA, Zieba J, Suchy S, Senderowicz L, Victorsen A, Bild NA, Grundstad AJ, Hanley D, MacAlpine DM, Mannervik M, Venken K, Bellen H, White R, Gerstein M, Russell S, Grossman RL, Ren B, Posakony JW, Kellis M, White KP. A cis-regulatory map of the Drosophila genome. Nature. 2011 Mar 24;471(7339):527-31. (PubMed)
Petre, I., C.L. Hyder, A. Mizera, A. Meinander, A. Mikhailov, R.I. Morimoto, L. Sistonen, J.E. Eriksson, and R-J. Back. A Simple Mass-Action Model for the Eukaryotic Heat Shock Response and its Mathematic Validation. Natural Computing. 2011 10: 595-612. (SpringerLink)
Prahlad V, Morimoto RI. Neuronal circuitry regulates the response of Caenorhabditis elegans to misfolded proteins. Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14204-9. (PubMed)
Puckelwartz M, McNally EM. Emery-Dreifuss muscular dystrophy. Handb Clin Neurol. 2011;101:155-66. (PubMed)
Quan J, Saaem I, Tang N, Ma S, Negre N, Gong H, White KP, Tian J. Parallel on-chip gene synthesis and application to optimization of protein expression. Nat Biotechnol. 2011 May;29(5):449-52. (PubMed)
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