The mission of the Chicago Biomedical Consortium is to stimulate collaboration among scientists at Northwestern University, the University of Chicago, and the University of Illinois at Chicago that will transform research at the frontiers of biomedicine.

Science spotlight

High-throughput screen promises to combat C. difficile

The CBC team of Arnon Lavie and Michael Caffrey from UIC and Wayne Anderson from NU received a CBC High Throughput Screening (HTS) Supplemental Grant in June 2013. On February 21, 2014, the team’s results, entitled “Discovery of Selective Inhibitors of the Clostridium difficile Dehydroquinate Dehydratase,” were published in PLoS One. Using a HTS screening facility at UIC, the team identified three new compounds that have the potential to become novel antibiotics to fight the notoriously difficult to treat and often life-threatening gastrointestinal infections caused by the bacterium Clostridium difficile. The paper represents the first success story coming out of the CBC HTS Award program.
(more info)



April 18, 2014
How Immune Cells Tell Healthy And Diseased Cells Apart

Greg Titjen, PhD, was selected as a CBC Scholar in 2012, when he was a PhD student in the Department of Biophysical Sciences & Institute for Biophysical Dynamics at the University of Chicago. He was supervised by two co-mentors, Erin Adams, associate professor of biochemistry and molecular biophysics (specializing in the immune system), and Ka Yee Lee, professor of chemistry. This unique collaboration enabled Greg to comprehensively study the role of the cell membranes lipids in the process of immunorecognition. Greg's results were published in the March 31, 2014 issue of PNAS: “Molecular mechanism for differential recognition of membrane phosphatidylserine by the immune regulatory receptor Tim4.”
(more info)

April 15, 2014
Fifth Annual CBC Scholars Scientific Exchange

The Fifth Annual CBC Scholars Scientific Exchange was held on March 28, 2014. Sixteen CBC Scholars gathered downtown Chicago at the University of Chicago Gleacher Center for the annual all day meeting.
(more info)

April 7, 2014
”Bringing STEM Home” – CBC Scholars volunteer at 64th Annual CPS Science Fair

Once again, members of the CBC Scholars Program volunteered their time and knowledge to help judge at the 64th Annual Chicago Public Schools (CPS) Science Fair held on March 23rd, 2014 at the Museum of Science and Industry.
(more info)

(more news)
(archives of the announcements and news highlights)


CBC Tech Day: Cutting-Edge Technologies — Driving Science Forward

The CBC Tech Day, entitled "Cutting-Edge Technologies — Driving Science Forward" will take place on June 16, 2014, at the Prentice Women's Hospital at the Northwestern University Chicago Campus. Program and registration details coming up soon.
(more info)


Today at NU, UChicago & UIC

TODAY is Monday, April 21, 2014

12:00 PM
UIC Department of Microbiology and Immunology
Alexander Mankin, Ph.D., University of Illinois at Chicago
Encounters of nascent peptides and antibiotics in the exit tunnel of the ribosome

4:00 PM
NU Institute for BioNanotechnology in Medicine
John A. Kessler, Northwestern University Feinberg School of Medicine


(more events)