The mission of the Chicago Biomedical Consortium is to stimulate collaboration among scientists at Northwestern University, the University of Chicago, and the University of Illinois at Chicago that will transform research at the frontiers of biomedicine.

Science spotlight

High-throughput screen promises to combat C. difficile

The CBC team of Arnon Lavie and Michael Caffrey from UIC and Wayne Anderson from NU received a CBC High Throughput Screening (HTS) Supplemental Grant in June 2013. On February 21, 2014, the team’s results, entitled “Discovery of Selective Inhibitors of the Clostridium difficile Dehydroquinate Dehydratase,” were published in PLoS One. Using a HTS screening facility at UIC, the team identified three new compounds that have the potential to become novel antibiotics to fight the notoriously difficult to treat and often life-threatening gastrointestinal infections caused by the bacterium Clostridium difficile. The paper represents the first success story coming out of the CBC HTS Award program.
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April 18, 2014
How Immune Cells Tell Healthy And Diseased Cells Apart

Greg Titjen, PhD, was selected as a CBC Scholar in 2012, when he was a graduate student in the Department of Biophysical Sciences & Institute for Biophysical Dynamics at the University of Chicago. He was supervised by two co-mentors, Erin Adams, associate professor of biochemistry and molecular biophysics (specializing in the immune system), and Ka Yee Lee, professor of chemistry. This unique collaboration enabled Greg to comprehensively study the role of the cell membranes lipids in the process of immunorecognition. Greg's results were published in the March 31, 2014 issue of PNAS: “Molecular mechanism for differential recognition of membrane phosphatidylserine by the immune regulatory receptor Tim4.”
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April 15, 2014
Fifth Annual CBC Scholars Scientific Exchange

The Fifth Annual CBC Scholars Scientific Exchange was held on March 28, 2014. Sixteen CBC Scholars gathered downtown Chicago at the University of Chicago Gleacher Center for the annual all day meeting.
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April 7, 2014
”Bringing STEM Home” – CBC Scholars volunteer at 64th Annual CPS Science Fair

Once again, members of the CBC Scholars Program volunteered their time and knowledge to help judge at the 64th Annual Chicago Public Schools (CPS) Science Fair held on March 23rd, 2014 at the Museum of Science and Industry.
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(archives of the announcements and news highlights)


Registration open for CBC Tech Day:
Cutting-Edge Technologies — Driving Science Forward

CBC Tech Day, "Cutting-Edge Technologies — Driving Science Forward" will take place on June 16, 2014, at Prentice Women's Hospital on Northwestern University's Chicago Campus. Online registration and poster abstract submission are now open and will close at 5 PM, Friday, May 23, 2014. For program and registration details click here.


Today at NU, UChicago & UIC

TODAY is Thursday, April 24, 2014

8:30 AM
NU McCormick-Chemical and Biological Engineering (Student Talk)
Brian Fritz, PhD candidiate from the Shea/Jewett Lab, Northwestern University
In Vitro Ribosome Construction for Ribosome Engineering

8:30 AM
NU Feinberg Cardiovascular Research Institute
Dean Y. Li, MD, PhD, University of Utah
Inflammation, Vascular Stability and Cancer

9:00 AM
NU McCormick-Chemical and Biological Engineering (Student Talk)
Alaina Schlinker, PhD candidiate from the Miller, Northwestern University
Generation and Separation of In Vitro-Derived Platelets

12:00 PM
UChicago Department of Pediatrics
Paul A. Offit, MD , University of Pennsylvania School of Medicine, Children’s Hospital of Philadelphia
Alternative Medicine: Sense or Nonsense

12:00 PM
UChicago Committee on Neurobiology
Huaxi Xu, Ph.D., Sanford-Burnham Medical Research Institute
Novel genes and pathways involved in Down Syndrome, Alzheimer's disease and Progressive Supranuclear Palsy

12:00 PM
UChicago Department of Pathology
Charles Van Slambrouck, M.D., Heewon (Aimee) Kwak, M.D.,Lindsay Alpert, M.D. and Thuy Can, M.D. , University of Chicago
Pathobiology Seminar Series

12:00 PM
NU Institute for Public Health and Medicine (IPHAM)
Jacek Topczewski, PhD and Jolanta Topczewska, PhD, Northwestern University
Zebrafish as a Model Organism for Pediatric Research

12:30 PM
NU Molecular Biosciences
Rebecca Heald, PhD, Univerity of California-Berkeley
Mechanisms of mitosis and size control in Xenopus

3:00 PM
UChicago Department of Medicine, Section of Nephrology
Arlene Chapman, MD, Emory University
Biomarker development in Nephrology: Examples from ADPKD

3:00 PM
UIC Center for Clinical and Translational Sciences
Professor Nicholas J. Wald, Barts and the London School of Medicine, University of London
Reversing the Global Cardiovascular Disease Epidemic

4:00 PM
NU Chemistry of Life Processes Institute
Michael Pollastri, Northwestern University
Synthetic chemistry and drug discovery

4:00 PM
NU McCormick - Biomedical Engineering Department
David Mogul, PhD, Illinois Institute of Technology
Using Endogenous Brain Synchrony Dynamics to Improve the Efficacy of Deep Brain Stimulation for Treating Epilepsy

7:30 PM
UChicago Committee on Evolutionary Biology
Jukka Jernvall, PhD, University of Helsinki
Playing with evolutionary transitions from the fossil record


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