The mission of the Chicago Biomedical Consortium (CBC) is to stimulate collaboration among scientists at Northwestern University, The University of Chicago, the University of Illinois at Chicago and others to accelerate discovery that will transform biomedical research and improve the health of humankind.
The CBC gratefully acknowledges support from the Searle Funds at The Chicago Community Trust.

February 26, 2018
CBC is inviting new applications for the Accelerator Award program

Accelerator Award is a milestone-driven award program ($100,000 for 1st year) focused on translational research toward therapeutics or associated biomarkers and diagnostics.

Fall 2018 round Letter of Intent (LOI) submissions open at 8:00 AM on June 4, 2018 and close at 5:00 PM on June 8, 2018.

If you plan to apply, please make sure that you are conforming to the MOST RECENT RFA. Applications not conforming to the specified guidelines will NOT be accepted. In addition, applicants, if selected, MUST be available to present their projects at a CBCAN meeting on August 2 and/or August 16, 2018. Both meetings will be held on a Thursday, from 4:00-7:00 PM, at Prentice Women Hospital Conference Center downtown Chicago. MARK YOUR CALENDARS!

▸ Program description
▸ RFA (Please make sure that you are conforming to the MOST RECENT RFA.)

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CBC on Twitter

March 16, 2018
The promise of increased sensitivity for early cancer detection and management being realized by Vadim Backman and Tom O’Halloran, NU, with the help of instrumentation and a core facility supported by a CBC Lever Award

CBC is happy to share an article in which Vadim Backman, NU, is profiled by Clare Milliken, for the Northwestern Now (see below). Backman is part of the most recent CBC Lever team, awarded in 2015 for the project: “Chicago Center for Physical Science-Oncology Innovation and Translation.” Additional investigators include Lucy Godley, UChicago and Jack Kaplan, UIC. The $1.5 million CBC Lever was awarded in conjunction with a $10 million U54 grant from the National Cancer Institute to fund the Chicago Region Physical Science-Oncology Center (CR-PSOC), led by led by Thomas V. O’Halloran and Jonathan D. Licht, NU. The goal of CR-PSOC is to advance the understanding of carcinogenesis by examining the role of physical and chemical forces involved in the transformation of a normal cell into a cancerous one. CBC Lever Award funds were designated in part to support the Nanocytometry Core, led by Backman, including the Partial Wave Spectroscopy (PWS) — methodology developed by Backman and prominently featured in the article below. CBC is proud to have contributed to important advances in the field of cancer diagnostics and treatment. Congratulations to all CBC Lever team members!

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March 15, 2018
Fluidigm CyTOF-2 Mass Cytometer, hosted by the lab of a past member of the CBC Catalyst Review Board, Anne Sperling, UChicago, helps in study of idiopathic pulmonary fibrosis (IPF)

Sonia Mohinta is a postdoctoral scholar at UChicago, and an immunologist interested in understanding the complex role of regulatory T cells (Tregs) in IPF disease pathology. She recently wrote an article for the UChicago Medicine, At the Forefront (see below), where she discusses the IPF characteristics and points out how little is still known about this quickly devastating and fatal disease. To further understand how Tregs contribute to the course of the disease, Sonia describes research approaches she has undertaken during her postdoctoral work at UChicago. One of them relies on access to the CyTOF (cytometry by time-of-flight) in the lab of Anne Sperling, UChicago. Sperling, who is also director of Flow Cytometry Core at UChicago, served on the CBC Catalyst Review Board for four years (2013-2017). The CBC is thankful for Anne’s service and wishes her all the best in her scientific endeavors at UChicago.

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March 15, 2018
CRISPR then, now and in the future — three current and past NU scientists with multiple links to CBC: Elizabeth McNally, Navdeep Chandel and Eric Sontheimer

In the article cited below, originally published in the Northwestern Medicine Magazine, Will Doss describes the parallels between the local (Northwestern-centric) and global history of CRISPR Cas9 gene editing methodology. Doss takes a reader on a captivating journey, full of fascinating examples and anecdotes, from the time of CRISPR discovery to futuristic applications that carry a potential to eradicate diseases that are currently untreatable. Among the NU scientists who were taken by the “CRISPR storm” in their research and are featured in the article are three CBC scientists: Elizabeth McNally, Navdeep Chandel and Eric Sontheimer (at UMMS now). Enjoy the read and, following the article, check out the impressive list of the ties these three scientists have with CBC! Congratulations to all featured researchers!

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March 13, 2018
Director’s Corner
Connecting with my past and celebrating the chemistry of the future at the Lilly Grantee Symposium

Yesterday I had the pleasure of attending the 18th Biennial Lilly Grantee Symposium in Chemistry. (…) The Grantee program is the oldest of its type across pharma, although there are now a number of prestigious pharma chemistry awards that parallel the original Lilly Grantee program. Started in 1965, the award recognizes, celebrates and supports academic chemists early in their career, prior to gaining tenure, and provides them with a 2-year unrestricted grant to enable them to better take the scientific risks necessary to advance the field and establish themselves across the community. The Symposium brings together the most recent grantees, along with a distinguished alumnus of the program for a day to celebrate chemistry writ large.
Jim Audia

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Featured Events

April 11, 2018
UChicago Department of Neurobiology
The 2018 Carlson Symposium on Neuroscience: Motor Circuits in Health and Disease

April 25-26, 2018
UChicago Computation Institute
GlobusWorld 2018: Connecting your Research Universe

May 10, 2018
NU Cognitive Neurology and Alzheimer’s Disease Center
24th Annual Alzheimer Day

May 16, 2018
UChicago Computation Institute
Future Compute: A Celebration of the Computation Institute

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Biotech & Entrepreneurship

March 20, 2018
SmartHealth Activator & Rosalind Franklin University of Medicine and Science
BioPathways Entrepreneurial Speaker Series

BioPathways: Fast-tracking Drug Repurposing for New Treatments of Life-threatening Diseases; Featuring Dr. Bruce Bloom, CEO, Cures Within Reach
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March 22, 2018
Women in Bio (WiB) – Chicago Chapter
Diversity & Inclusion in Health and Life Sciences: Where are we today?

Research supporting the business case for diversity in the workplace continues to grow. Yet, it is widely accepted that diversity is lacking in the health and life science sectors. Indeed, recent studies highlight that the gender gap in boardrooms and C-suites is among the highest in the health and life sciences as compared to other industries. Join our panel of executive women to explore why these gaps exist and what we and our organizations can do to make a change.
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