The mission of the Chicago Biomedical Consortium (CBC) is to stimulate collaboration among scientists at Northwestern University, The University of Chicago, the University of Illinois at Chicago and others to accelerate discovery that will transform biomedical research and improve the health of humankind.
The CBC gratefully acknowledges support from the Searle Funds at The Chicago Community Trust.

January 16, 2018
CBC is inviting new applications for the Catalyst Award program

One-time incentive awards (up to $250,000), focused on basic biological/biomedical or translational research, made to teams with principals and other strong representation from at least two of the CBC institutions.

If you plan to apply, please make sure that you are conforming to the MOST RECENT RFA revised Jan. 16, 2018. Applications not conforming to the specified guidelines will NOT be accepted.

Spring 2018 round submissions open at 8:00 AM on February 19, 2018 and close at 5:00 PM on February 23, 2018.

▸ CBC Catalyst Award RFA, rev. Jan. 16, 2018

December 13, 2017
CBC Newsletter, vol. 24
CBC invites new applications for the Accelerator and Catalyst Award programs

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January 18, 2018
ClostraBio, a startup co-founded by UChicago scientists with ties to CBC, called a “promising, emerging venture”

Congratulations to Cathryn Nagler, PhD, Bunning Food Allergy Professor at UChicago. Her biotech company—ClostraBio—was recently highlighted in the UChicago News and in Crain’s Chicago Business (see below). Nagler’s work focuses on new therapeutics that could benefit patients with increasingly common food allergies. Prior work published in 2015 in The ISME Journal, “Lactobacillus rhamnosus GG-supplemented formula expands butyrate-producing bacterial strains in food allergic infants,” was partially supported by the CCSB/CBC Fellowship, awarded to Aly Azeem Khan—a postdoctoral fellow in her lab and co-author on the paper. This Fellows program was financed by the first CBC Lever Award (2008) to the Chicago Center for Systems Biology (CCSB). ClostrBio’s co-founder, Jeffery Hubbell, UChicago, is also a CBC awardee—he received a CBC HTS Award (2016).

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January 11, 2018
“Tag, You‘re It!” Tagging proteins with ubiquitin by different E3 ligases may be key to specificity of the ubiquitin-dependent protein degradation

In 2011, a collaboration between Hiroaki Kiyokawa, NU and Jun Yin, currently at Georgia State University but formerly at UChicago, led to a CBC Catalyst Award to “Identify Cell Cycle-Regulatory Substrates Ubiquitinated by the Apoptosis Inhibitor BRUCE.” In 2014, Kiyokawa and his postdoc, Xianpeng Liu, applied and received a CBC Postdoctoral Research Award to “Identify ubiquitination substrates specific for the non-canonical E1 enzyme UBA6.” Two recent publications in Nature Communications and in Science Advances resulted from the CBC funding. Yin and Kiyokawa are senior co-authors, and Liu a co-author on both publications. The papers describe a clever technology to study the role of distinct E3 ligases in the specificity of ubiquitin-dependent protein degradation, a process implicated in the pathology of many human diseases including cancer and autism. Congratulations to both teams!

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January 11, 2018
“Mind-plus-machine partnership” — a past CBC Scholar, Adam Pah, NU, encourages keeping up with the progress in machine learning and artificial intelligence

Adam Pah, clinical assistant professor of management and organizations, teaches an MBA course on Human-Machine Intelligence at the NU Kellogg School of Management. As a part of the Kellogg Architectures of Collaboration Initiative, the course is intended for the ever-growing cadre of MBA students who would employ machine learning in their future endeavors. Adam was a CBC Scholar, Class of 2011. He received his PhD in 2013 from the NU Department of Chemical and Biological Engineering, while working in Luis Amaral’s lab. Congratulations on a successful career!

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January 10, 2018
The CBC is proud to announce that over 2000 publications have been attributed to CBC funding! The winning 2000th publication will be announced soon! The publication will be featured on the CBC homepage and the CBC awardee(s) will receive a surprise gift to commemorate the occasion!

▸ CBC Publications

Featured Events

January 25, 2018
The Women’s Health Research Institute at NU
2nd Annual Symposium on Sex Inclusion in Biomedical Research: A Spotlight on Autoimmunity

April 25-26, 2018
UChicago Computation Institute
GlobusWorld 2018: Connecting your Research Universe

May 10, 2018
NU Cognitive Neurology and Alzheimer’s Disease Center
24th Annual Alzheimer Day

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Biotech & Entrepreneurship

January 16, 2018
SmartHealth Activator & Rosalind Franklin University of Medicine and Science
BioPathways: JP Morgan Aftermath – a corporate venture capital perspective for 2018; Featuring Scott Brun, abbvie.
▸ More info and registration details

January 30-31, 2018
SBIR/STTR Grant Writing Workshop

PROPEL is hosting this 2-day Intensive Workshop, provided by BBC Entrepreneurial Training & Consulting (BBCetc), that will cover all aspects of writing SBIR/STTR grants focused on life science technologies including: eligibility, sources of funding and agency differences, understanding what reviewers look for, step-by-step instruction on how to write each section of your proposal.
▸ More info and registration details

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