Updated: August 7, 2015
Leo Serebryannyy
CBC Scholar: Class of 2014
PhD Candidate, Department of Physiology and Biophysics, UIC
Advisor: Primal de Lanerolle
DE LANEROLLE LAB WEBPAGE
RESEARCH INTERESTS:
My research interests center on how the cytoskeleton regulates gene expression. Namely, I am interested in the roles of actin and actin binding proteins within the nucleus and their regulation of transcription and chromatin remodeling. Currently I am pursuing several avenues of investigation: how nuclear actin is a critical regulator of transcription and nuclear organization, how nuclear actin is regulated, and the pathological consequences of altered nuclear actin dynamics.
PUBLICATIONS:
Daugherty RL, Serebryannyy L, Yemelyanov A, Flozak AS, Yu HJ, Kosak ST, deLanerolle P, Gottardi CJ. α- Catenin is an inhibitor of transcription. Proc Natl Acad Sci U S A. 2014 Apr 8;111(14):5260-5. (PubMed)
#Yu HJ, #Serebryannyy LA, Fry M, Greene M, Chernaya O, Hu WY, Chew TL, Mahmud N, Kadkol SS, Glover S, Prins G, Strakova Z, de Lanerolle P. Tumor stiffness is unrelated to Myosin light chain phosphorylation in cancer cells. PLoS One. 2013 Nov 4;8(11):e79776. #Indicates equal contributions. (PubMed)
de Lanerolle P, Serebryannyy L. Nuclear actin and myosins: life without filaments. Nat Cell Biol. 2011 Nov 2;13(11):1282-8. (PubMed)
Tucker KR, Lanni EJ, Serebryannyy LA, Rubakhin SS, Sweedler JV. Stretched tissue mounting for MALDI mass spectrometry imaging. Anal Chem. 2011 Dec 1;83(23):9181-5. (PubMed)
Tucker KR, Serebryannyy LA, Zimmerman TA, Rubakhin SS, Sweedler JV. The modified-bead stretched sample method: development and application to MALDI-MS imaging of protein localization in the spinal cord. Chem Sci. 2011;2(4):785-795. (PubMed)
AWARDS AND HONORS:
- Chicago Biomedical Consortium (CBC) Scholar, 2014-2015
- American Heart Association Midwest Affiliate Pre-doctoral Fellowship, 2013-2015
- National Cancer Institute Physical Sciences-Oncology Young Investigator Trans-Network Project Award, 2013
- University of Illinois at Chicago Chancellor’s Graduate Fellowship, 2013
- University of Illinois at Chicago Student Presenter Award, 2013
- University of Illinois at Chicago Graduate Student Council Travel Award, 2013
- The American Society for Cell Biology Graduate Travel Award, 2013
- University of Illinois at Chicago W.C. and May Preble Deiss Award for Graduate Research, 2012
- UIC Dept. of Physiology and Biophysics Kate Barany Graduate Student Award, 2012
- UIC Dept. of Physiology and Biophysics Mark R. Lambrecht Award for Research, 2012
- National Science Foundation: Graduate Research Fellowship Program Honorable Mention, 2012
ACTIVITIES:
- Financial Officer and Co-founder of ‘GEMS’ Gives Back: a service organization for graduate students in the medical sciences at UIC
- Graduate Student Representative for the Dept. of Physiology and Biophysics, UIC
- Class Instructor for Physiology 310: Summer Pre-matriculation Physiology, UIC