This is a list of all submitted CBC Catalyst Applications beginning with Round 32 (created October 3, 2022). If this review platform continues to be used for the future Catalyst Application rounds, please follow the application submission dates to discern between the cycles.
Applications are listed by the entry ID# (Application ID#); in a descending order (most recent on top).
Application #: 14
Entry ID#: 724
Submitted: November 12, 2022 at 12:21 PM
PI #1: Marsha Rosner, PhD, Professor, UChicago
Email: mrosner@uchicago.edu
PI #2: Guido Pauli, PhD, Professor, UIC
Email: gfp@uic.edu
Proposal Title: Characterization of Cannabidiol and Congeneric Cannabinoids as Inducers of Interferons
Key Words: Cannabinoids, CBD, interferons, SARS-CoV-2
Amount Requested: 250000.00
Application (PDF): ▸ Characterization of Cannabidiol and Congeneric Cannabinoids as Inducers of Interferons
Application #: 14
Entry ID#: 730
Submitted: November 17, 2022 at 11:56 AM
PI #1: Megan McNerney, MD/PhD, Associate Professor, UChicago
Email: Megan.McNerney@bsd.uchicago.edu
PI #2: Feng Yue, PhD, Professor, Northwestern
Email: yue@northwestern.edu
Proposal Title: Determining the role of CUX1 in genome architecture
Key Words: 3D architecture, cancer genomics, tumor suppressor gene, myeloid malignancies
Amount Requested: 250000.00
Application (PDF): ▸ Determining the role of CUX1 in genome architecture
Application #: 14
Entry ID#: 734
Submitted: November 18, 2022 at 9:40 AM
PI #1: Anita Chong, PhD, Professor, UChicago
Email: achong@uchicago.edu
PI #2: Anat Tambur, PhD, Research Professor, Northwestern
Email: a-tambur@northwestern.edu
Proposal Title: Autoreactive IgG as biomarkers of transplantation rejection
Key Words: transplantation, rejection, autoantibodies, diagnosis, biomarkers
Amount Requested: 250000.00
Application (PDF): ▸ Autoreactive IgG as biomarkers of transplantation rejection
Application #: 14
Entry ID#: 735
Submitted: November 18, 2022 at 10:05 AM
PI #1: Joseph Zak, PhD, Assistant Professor, UIC
Email: jdzak@uic.edu
PI #2: Leslie Kay, PhD, Professor, UChicago
Email: lkay@uchicago.edu
Proposal Title: Neural mechanisms of sensory hypersensitivity in autism spectrum disorders
Key Words: Autism, Sensory Systems, Hypersensitivity, Electrophysiology, Odors
Amount Requested: 250000
Application (PDF): ▸ Neural mechanisms of sensory hypersensitivity in autism spectrum disorders
Application #: 14
Entry ID#: 736
Submitted: November 18, 2022 at 12:10 PM
PI #1: Jeffrey Hubbell, PhD, Professor, UChicago
Email: jhubbell@uchicago.edu
PI #2: Stephanie Eisenbarth, MD/PhD, Professor, Northwestern
Email: stephanie.eisenbarth@northwestern.edu
Proposal Title: Novel strategies to drive antigen specific tolerance against respiratory allergens in asthma
Key Words: tolerance, asthma, allergen, immunotherapy, therapeutic
Amount Requested: 249999
Application (PDF): ▸ Novel strategies to drive antigen specific tolerance against respiratory allergens in asthma
Application #: 14
Entry ID#: 737
Submitted: November 18, 2022 at 12:28 PM
PI #1: Jonathan Coloff, PhD, Assistant Professor, UIC
Email: coloff@uic.edu
PI #2: Alexander Muir, PhD, Assistant Professor, UChicago
Email: amuir@uchicago.edu
Proposal Title: Improving Triple-Negative Breast Cancer Therapy by Targeting the Tumor Microenvironment
Key Words: breast cancer, metabolism, tumor microenvironment, chemotherapy, nutrition
Amount Requested: 250000
Application (PDF): ▸ Improving Triple-Negative Breast Cancer Therapy by Targeting the Tumor Microenvironment
Application #: 14
Entry ID#: 738
Submitted: November 18, 2022 at 1:31 PM
PI #1: Ying Hu, PhD, Assistant Professor, UIC
Email: yshu@uic.edu
PI #2: Adam Lin, MD/PhD, Assistant Professor, Northwestern
Email: adam.lin@northwestern.edu
Proposal Title: Prognostic Imaging of T Cell Health (PITCH) for CAR T Therapy
Key Words: Imaging, T cell, CAR T therapy, Calcium, Bioengineering
Amount Requested: 250000
Application (PDF): ▸ Prognostic Imaging of T Cell Health (PITCH) for CAR T Therapy
Application #: 14
Entry ID#: 739
Submitted: November 18, 2022 at 2:57 PM
PI #1: Manyuan Long, Ph.D., Edna K Papazian Distinguished Service Professor, UChicago
Email: mlong@uchicago.edu
PI #2: Jie Liang, Ph.D., Richard and Loan Hill Professor, UIC
Email: jliang@uic.edu
Proposal Title: FUNCTIONS AND ORIGINS OF NEW COMPONENTS IN THE CCR4-NOT DEADENYLASE COMPLEX IN DROSOPHILA
Key Words: CCR4-NOT, Deadenylase, gene duplicates, alphaFold, protein interaction
Amount Requested: 250000.00
Application (PDF): ▸ FUNCTIONS AND ORIGINS OF NEW COMPONENTS IN THE CCR4-NOT DEADENYLASE COMPLEX IN DROSOPHILA
Application #: 14
Entry ID#: 740
Submitted: November 18, 2022 at 3:19 PM
PI #1: Christian Peters, PhD, Assistant Professor, UIC
Email: cjpeters@uic.edu
PI #2: William Green, PhD, Professor, UChicago
Email: wgreen@bsd.uchicago.edu
Proposal Title: Mu-opioid receptor regulation by Golgi satellites in opioid use disorder
Key Words: opioid use disorder, opioid receptors, Golgi satellites
Amount Requested: 248400.00
Application (PDF): ▸ Mu-opioid receptor regulation by Golgi satellites in opioid use disorder
Application #: 14
Entry ID#: 741
Submitted: November 18, 2022 at 3:46 PM
PI #1: Juan Mendoza, PhD, Assistant Professor, UChicago
Email: jlmendoza@uchicago.edu
PI #2: Curt Horvath, PhD, Professor, Northwestern
Email: horvath@northwestern.edu
Proposal Title: Modulating the potency of cytokine signaling by optimizing receptor-kinase engagement
Key Words: Cytokines, screens, drugs, cancer, virus, potentiation
Amount Requested: 250000
Application (PDF): ▸ Modulating the potency of cytokine signaling by optimizing receptor-kinase engagement
Application #: 14
Entry ID#: 742
Submitted: November 18, 2022 at 3:54 PM
PI #1: Jan-Hendrik Spille, Dr., Assistant Professor, UIC
Email: jhspille@uic.edu
PI #2: Alexander Ruthenburg, PhD, Associate Professor, UChicago
Email: aruthenburg@uchicago.edu
Proposal Title: Novel tools for quantitative mapping of epigenetic and structural remodeling of eukaryotic chromatin
Key Words: chromatin organization, epigenetics, molecular mechanisms, super-resolution microscopy, genomics
Amount Requested: 250000.00
Application (PDF): ▸ Novel tools for quantitative mapping of epigenetic and structural remodeling of eukaryotic chromatin
Application #: 14
Entry ID#: 743
Submitted: November 18, 2022 at 4:08 PM
PI #1: Hojoon Lee, PhD, Assistant Professor, NU
Email: hojoon.lee@northwestern.edu
PI #2: Raymond Moellering, PhD, Associate Professor, UChicago
Email: rmoellering@uchicago.edu
Proposal Title: Ultrasensitive Discovery of Circulating Nausea-Inducing Factors
Key Words: Proteomics, Metabolomics, Nausea, Motion Sickness, Cerebral Spinal Fluid
Amount Requested: 250000.00
Application (PDF): ▸ Ultrasensitive Discovery of Circulating Nausea-Inducing Factors
Application #: 14
Entry ID#: 745
Submitted: November 18, 2022 at 4:58 PM
PI #1: Preston Snee, PhD, Associate Professor, UIC
Email: sneep@uic.edu
PI #2: Ankit Bharat, MD/PhD, Professor, Northwestern
Email: ankit.bharat@nm.org
Proposal Title: Cell-penetrating quantum dots for lung transplant assay
Key Words: quantum dot, transplant, nanotechnology, imaging, immunology
Amount Requested: 232752.00
Application (PDF): ▸ Cell-penetrating quantum dots for lung transplant assay
Application #: 14
Entry ID#: 746
Submitted: November 18, 2022 at 4:59 PM
PI #1: Ian Papautsky, PhD, Professor, UIC
Email: papauts@uic.edu
PI #2: Anindita Basu, PhD, Assistant Professor, UChicago
Email: onibasu@uchicago.edu
Proposal Title: Advanced microfluidic model of lung cancer for precision drug therapy
Key Words: microfluidics, lung cancer, single cell analysis
Amount Requested: 250000.00
Application (PDF): ▸ Advanced microfluidic model of lung cancer for precision drug therapy